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GTX27970 IHC-P Image
GTX27970 IHC-P Image
GTX27970 IHC-P Image

NFkB p65 antibody

Research Use Only
GTX27970
GeneTex
ApplicationsGel Shift Assay, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    NFkB p65 antibody
  • Delivery Days Customer
    10
  • Applications
    Gel Shift Assay, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstroem macroglobulinemia and does not correlate with p65 NF-kappaB activation. Merzianu M et al., 2006 Jul, Mod Pathol
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  • Sustained inflammation due to nuclear factor-kappa B activation in irradiated human arteries. Halle M et al., 2010 Mar 23, J Am Coll Cardiol
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  • Systemic inflammation activates the nuclear factor-kappaB regulatory pathway in adipose tissue. Ekstroem M et al., 2010 Aug, Am J Physiol Endocrinol Metab
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