NKCC2 antibody, PAb (ATTO-390)
ORB152673
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierBiorbyt
- Product NameNKCC2 antibody, PAb (ATTO-390)
- Delivery Days Customer10
- ApplicationsWestern Blot, ImmunoHistoChemistry
- Applications SupplierWB (1:1000); IHC (1:25) WB, IHC
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateAtto 390
- HostRabbit
- Scientific DescriptionRabbit polyclonal to NKCC2 (ATTO-390). NKCC2, a kidney-specific member of the cation chloride co-transporter family SLC12, facilitates transport of sodium, potassium, and chloride ions from the lumen of the renal thick ascending limb into the cell. Transport of sodium dilutes the luminal fluid, decreasing its osmolality creating an osmotic driving force for water reabsorption in the connecting tubule and cortical collecting duct under the influence of the hormone vasopressin. NKCC2 is found on the apical surface of the thick ascending limb of the loop of Henle and is blocked by loop diuretics such as furosemide..
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203