Bio-Connect

NOTCH4 antibody, PAb

Research Use Only
ORB67113
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    NOTCH4 antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:500-1:2000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to NOTCH4.Neurogenic locus notch homolog protein 4 (NOTCH4) is a single pass membrane protein that belongsto the NOTCH family. NOTCH4 functions as a receptor for membrane-bound ligands Jagged1,Jagged2 and Delta1 to regulate cell-fate determination. NOTCH4 is cleaved upon ligand activationand the notch intracellular domain (NICD) is released, which forms a transcriptional activator complexwith RBPJ/RBPSUH to activate genes of the enhancer of split locus. It affects the implementation ofdifferentiation, proliferation and apoptotic programs.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203