NSE Antibody / Neuron Specific Enolase
ORB386134
Overview
- SupplierBiorbyt
- Product NameNSE Antibody / Neuron Specific Enolase
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierWestern blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.2-0.4ug/ml for 30 min at RT IHC-P, WB
- CertificationResearch Use Only
- Clone IDENO2/1375
- IsotypeIgG
- Scientific DescriptionRecognizes a protein of about 50kDa, which is identified as gamma-Enolase/Neuron Specific Enolase/Enolase 2. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue and gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
- UNSPSC12352203