Overview
- SupplierGeneTex
- Product NameOccludin antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.98 mg/ml
- Gene ID100506658
- Target nameOCLN
- Target descriptionoccludin
- Target synonymsBLCPMG; occludin; phosphatase 1, regulatory subunit 115; PPP1R115; PTORCH1
- IsotypeIgG
- Scientific DescriptionThis gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- CircLphn3 protects the blood-brain barrier in traumatic brain injury. Cheng YQ et al., 2022 Apr, Neural Regen ResRead more
- Conditioned medium from LS 174T goblet cells treated with oxyresveratrol strengthens tight junctions in Caco-2 cells. Hwang D et al., 2017 Jan, Biomed PharmacotherRead more
- Flash Fabrication of Orally Targeted Nanocomplexes for Improved Transport of Salmon Calcitonin across the Intestine. Sun L et al., 2020 Mar 2, Mol PharmRead more
- Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota. Zhang LY et al., 2020, Evid Based Complement Alternat MedRead more
- Oxyresveratrol improves tight junction integrity through the PKC and MAPK signaling pathways in Caco-2 cells. Jo H et al., 2017 Oct, Food Chem ToxicolRead more
- Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: Involvement of the gut-brain axis. Petrella C et al., 2021 Oct, Pharmacol ResRead more
- Resveratrol reduces cerebral edema through inhibition of de novo SUR1 expression induced after focal ischemia. Alquisiras-Burgos I et al., 2020 Aug, Exp NeurolRead more
- Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin. He Z et al., 2017 Jun, BiomaterialsRead more