GTX105124 IHC-P Image
GTX105124 IHC-P Image
OGDH antibody [C2C3], C-term
GTX105124
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameOGDH antibody [C2C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.3 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the alpha-Ketoglutarate Signaling Pathway. Tseng CW et al., 2018 Jun 1, Cancer ResRead more
- alpha-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis. Atlante S et al., 2018 Jul 9, Cell Death DisRead more