OLR1 / LOX-1 antibody

Catalog number: GTX59636_100ug
Brand: GeneTex
Packing: 100 ug
Price: € 519.00
Expected delivery time: 10 days
Quantity:
GTX59636 WB Image
GTX59636 WB Image...

Product specifications for - OLR1 / LOX-1 antibody

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoHistoChemistry; Western Blot
Species: Human, Mouse, Rat
Host: Rabbit
Target: OLR1
Target description: oxidized low density lipoprotein receptor 1
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.5 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Gene ID: 4973
Swiss prot ID: P78380
Additional information: 
Synonyms: GTX_citation; CLEC8A; C-type lectin domain family 8 member A; hLOX-1; Lectin-like oxidized LDL receptor 1; lectin-type oxidized LDL receptor 1; LOX1; LOXIN; ox LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; SCARE1; scavenger receptor class E, member 1; SLOX1
"Oxidized low-density lipoprotein (oxLDL) affects load-free cell shortening of cardiomyocytes in a proprotein convertase subtilisin/kexin 9 (PCSK9)-dependent way." Schluter KD et al., 2017 Sep 14, Basic Res Cardiol Read more