Overview
- SupplierGeneTex
- Product NameOTC antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells. Agrawal V et al., 2012 Jan, Anticancer DrugsRead more
- Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice. Wang X et al., 2018 Sep 1, J NutrRead more
- Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency. Sugahara G et al., 2021 May, J Inherit Metab DisRead more