GTX83950 FACS Image
PAICS antibody [2C9] - Overexpression Validated
GTX83950
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Overview
- SupplierGeneTex
- Product NamePAICS antibody [2C9] - Overexpression Validated
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2C9
- Concentration0.63 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression. Chakravarthi BVSK et al., 2018 Sep, NeoplasiaRead more
- Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer. Chakravarthi BV et al., 2017 Jan, ProstateRead more
- Lentivirus-mediated CDglyTK gene-modified free flaps by intra-artery perfusion show targeted therapeutic efficacy in rat model of breast cancer. Zhang J et al., 2019 Sep 14, BMC CancerRead more
- PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression. Agarwal S et al., 2020 Jul, Transl OncolRead more
- PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer. Agarwal S et al., 2020 Mar 25, Cancers (Basel)Read more