Bio-Connect
GTX83950 FACS Image
GTX83950 FACS Image
GTX83950 FACS Image

PAICS antibody [2C9] - Overexpression Validated

Research Use Only
GTX83950
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    PAICS antibody [2C9] - Overexpression Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    2C9
  • Concentration
    0.63 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression. Chakravarthi BVSK et al., 2018 Sep, Neoplasia
    Read more
  • Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer. Chakravarthi BV et al., 2017 Jan, Prostate
    Read more
  • Lentivirus-mediated CDglyTK gene-modified free flaps by intra-artery perfusion show targeted therapeutic efficacy in rat model of breast cancer. Zhang J et al., 2019 Sep 14, BMC Cancer
    Read more
  • PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression. Agarwal S et al., 2020 Jul, Transl Oncol
    Read more
  • PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer. Agarwal S et al., 2020 Mar 25, Cancers (Basel)
    Read more