PARC Antibody

GeneTex

PARC Antibody

10

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

85 mg/ml

Rabbit

IgG

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. PARC is a cullin family member that functions as a cytoplasmic anchor protein in p53-associated protein complexes. PARC regulates the subcellular localization of p53 and subsequent function. PARC forms a complex with p53 in the cytoplasm of unstressed cells and interacts with UBCH7 and UBCH8. PARC shows a cytoplasmic localization and is ubiquitously expressed in all tissues with highest expression in testis brain and kidney.

Human

2°C to 8°C,-20°C

12352203