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GTX100573 WB Image
GTX100573 WB Image
GTX100573 WB Image

PARP antibody

Research Use Only
GTX100573
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    PARP antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.3 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A Tangeretin Derivative Inhibits the Growth of Human Prostate Cancer LNCaP Cells by Epigenetically Restoring p21 Gene Expression and Inhibiting Cancer Stem-like Cell Proliferation. Wei GJ et al., 2019 Jul 10, AAPS J
    Read more
  • An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation. Shindo Y et al., 2016 Jul 4, Sci Rep
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  • Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro. Chin YT et al., 2014 Dec 30, Oncotarget
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  • Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species. Lee CW et al., 2019 Aug, J Cell Physiol
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  • Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy. Luo LF et al., 2021, Front Pharmacol
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  • Autophagy inhibition enhances isorhamnetin-induced mitochondria-dependent apoptosis in non-small cell lung cancer cells. Ruan Y et al., 2015 Oct, Mol Med Rep
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  • Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCalpha-mediated AHR-HDAC interactions. Tsai CH et al., 2020 Feb, Biochim Biophys Acta Mol Cell Res
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  • Biliverdins regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer. Zheng J et al., 2014 Apr 15, Br J Cancer
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  • Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Chakraborty A et al., 2016 Oct 5, Nat Commun
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  • CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells. Inturi R et al., 2021 Oct, Virology
    Read more