GTX112864 WB Image
GTX112864 WB Image
PARP antibody [N2C1], Internal
GTX112864
Product group Antibodies
Overview
- SupplierGeneTex
- Product NamePARP antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.28 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- LNX1 Contributes to Cell Cycle Progression and Cisplatin Resistance. Jang M et al., 2021 Aug 12, Cancers (Basel)Read more
- A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat MethodsRead more
- GSK3beta negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons. Chien T et al., 2018 Dec, Mol PsychiatryRead more
- PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression. Doersam B et al., 2018 Apr 24, Proc Natl Acad Sci U S ARead more
- Reactive oxygen species-driven mitochondrial injury induces apoptosis by teroxirone in human non-small cell lung cancer cells. Wang JP et al., 2017 Sep, Oncol LettRead more
- The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Chen PH et al., 2017 Apr, NeuropharmacologyRead more