PARP antibody [N2C1], Internal - KO/KD, Comparison, Orthogonal, Overexpression, IP/MS Validated | GTX112864 | 25 ul - Bio-Connect

General

Product specifications for - PARP antibody [N2C1], Internal - KO/KD, Comparison, Orthogonal, Overexpression, IP/MS Validated

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ChIP Chromatin ImmunoPrecipitation; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Species:	Human, Mouse, Rat
Host:	Rabbit
Target:	PARP1
Target description:	poly(ADP-ribose) polymerase 1
Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Controle:	293T , A431 , HeLa , HepG2 , HCT116 , HCT116 (30 microM cisplatin treatment for 24 hr) , NIH-3T3 , PC-12 , *H1299

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	0.11 mg/ml
Storage instructions:	Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.

Scientific information:
Scientific info:	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Gene ID:	142
Swiss prot ID:	P09874

Additional information:
Synonyms:	ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; PPOL