PARP antibody [N2C1], Internal - KO/KD, Comparison, Orthogonal, Overexpression, IP/MS Validated

Catalog number: GTX112864_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: 25 ul
Price: € 267.20
Expected delivery time: 10 days
Quantity:
GTX112864 ChIP assay Image
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Product specifications for - PARP antibody [N2C1], Internal - KO/KD, Comparison, Orthogonal, Overexpression, IP/MS Validated

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ChIP Chromatin ImmunoPrecipitation; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Species: Human, Mouse, Rat
Host: Rabbit
Target: PARP1
Target description: poly(ADP-ribose) polymerase 1
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Controle: 293T , A431 , HeLa , HepG2 , HCT116 , HCT116 (30 microM cisplatin treatment for 24 hr) , NIH-3T3 , PC-12 , *H1299
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 0.11 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Gene ID: 142
Swiss prot ID: P09874
Additional information: 
Synonyms: GTX_citation; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; PPOL
A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods Read more
GSK3beta negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons. Chien T et al., 2018 Dec, Mol Psychiatry Read more
Reactive oxygen species-driven mitochondrial injury induces apoptosis by teroxirone in human non-small cell lung cancer cells. Wang JP et al., 2017 Sep, Oncol Lett Read more
The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Chen PH et al., 2017 Apr, Neuropharmacology Read more