Overview
- SupplierGeneTex
- Product NamePAX6 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.92 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peters anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Manganas LN et al., 2021 Mar 10, Sci RepRead more
- Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. Yang SC et al., 2019 Sep, FASEB JRead more
- MicroRNA-328 may influence myopia development by mediating the PAX6 gene. Chen KC et al., 2012 May 31, Invest Ophthalmol Vis SciRead more
- Neural Progenitor-Like Cells Induced from Human Gingiva-Derived Mesenchymal Stem Cells Regulate Myelination of Schwann Cells in Rat Sciatic Nerve Regeneration. Zhang Q et al., 2017 Feb, Stem Cells Transl MedRead more
- OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Xu R et al., 2019 Jun 6, Cell Stem CellRead more
- Role of astroglia in Downs syndrome revealed by patient-derived human-induced pluripotent stem cells. Chen C et al., 2014 Jul 18, Nat CommunRead more
- SMN is required for the maintenance of embryonic stem cells and neuronal differentiation in mice. Chang WF et al., 2015, Brain Struct FunctRead more