Overview
- SupplierGeneTex
- Product NamePAX8 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.87 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Ovulatory Follicular Fluid Facilitates the Full Transformation Process for the Development of High-Grade Serous Carcinoma. Hsu CF et al., 2021 Jan 26, Cancers (Basel)Read more
- PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. Shi K et al., 2019 May 3, ElifeRead more
- PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression. Sun Z et al., 2019 Dec, Oncol LettRead more