Overview
- SupplierGeneTex
- Product NamePD-L1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.66 mg/ml
- IsotypeIgG
- Scientific DescriptionInvolved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A combination of anti-PD-L1 mAb plus Lm-LLO-E6 vaccine efficiently suppresses tumor growth and metastasis in HPV-infected cancers. Lin PL et al., 2017 Sep, Cancer MedRead more
- An increase in BAG-1 by PD-L1 confers resistance to tyrosine kinase inhibitor in non-small cell lung cancer via persistent activation of ERK signalling. Lin PL et al., 2017 Nov, Eur J CancerRead more
- Differential Expression and Clinicopathological Significance of HER2, Indoleamine 2,3-Dioxygenase and PD-L1 in Urothelial Carcinoma of the Bladder. Kim D et al., 2020 Apr 27, J Clin MedRead more
- Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Li CW et al., 2018 Feb 12, Cancer CellRead more
- High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma. Lin YM et al., 2015, PLoS OneRead more
- IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. Chan LC et al., 2019 Jul 15, J Clin InvestRead more
- Impact of FAK Expression on the Cytotoxic Effects of CIK Therapy in Triple-Negative Breast Cancer. Pan MR et al., 2019 Dec 30, Cancers (Basel)Read more
- Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. Wang LT et al., 2017 Aug 1, Cancer ResRead more
- Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Cha JH et al., 2018 Aug 16, Mol CellRead more
- NDAT Targets PI3K-Mediated PD-L1 Upregulation to Reduce Proliferation in Gefitinib-Resistant Colorectal Cancer. Huang TY et al., 2020 Aug 3, CellsRead more