PD-L2 antibody

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Product specifications for - PD-L2 antibody

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ELISA; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; Western Blot
Species:	Human, Mouse, Rat
Host:	Rabbit
Target:	PDCD1LG2
Target description:	programmed cell death 1 ligand 2
Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	1 mg/ml
Storage instructions:	2-¦C to 8-¦C, -20-¦C or -80-¦C

Scientific information:
Scientific info:	Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Gene ID:	80380
Swiss prot ID:	Q9BQ51

Additional information:
Synonyms:	B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; butyrophilin B7-DC; CD273; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDL2; PD-L2; programmed cell death 1 ligand 2; programmed death ligand 2

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Product specifications for - PD-L2 antibody