PD-L2 antibody

Catalog number: GTX85449_100ug
Brand: GeneTex
Packing: 100 ug
Price: € 463.00
Expected delivery time: 10 days
Quantity:
GTX85449 IHC-P Image
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GTX85449 IHC-P Image
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GTX85449 IHC-P Image
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GTX85449 WB Image
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Product specifications for - PD-L2 antibody

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; Western Blot
Species: Human, Mouse, Rat
Host: Rabbit
Target: PDCD1LG2
Target description: programmed cell death 1 ligand 2
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Gene ID: 80380
Swiss prot ID: Q9BQ51
Additional information: 
Synonyms: B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; butyrophilin B7-DC; CD273; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDL2; PD-L2; programmed cell death 1 ligand 2; programmed death ligand 2