PD1 antibody [NAT105]

Catalog number: GTX20256_500ul
Brand: GeneTex
Packing: 500 ul
Price: € 500.00
Expected delivery time: 10 days
Quantity:
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Product specifications for - PD1 antibody [NAT105]

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: Flow Cytometry; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Frozen; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Western Blot
Species: Human, Mouse
Host: Mouse
Target: PDCD1
Target description: programmed cell death 1
Clonality: Monoclonal
Conjugation: Unconjugated
Isotype: IgG1
Properties: 
Purity: Unpurified
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Clone ID: NAT105
Gene ID: 5133
Swiss prot ID: Q15116
Additional information: 
Synonyms: CD279; hPD-1; hPD-l; hSLE1; PD1; PD-1; programmed cell death 1 protein; programmed cell death protein 1; protein PD-1; SLEB2; systemic lupus erythematosus susceptibility 2
"Angioimmunoblastic T-cell lymphoma mice model." Sato F et al., 2013 Jan, Leuk Res Read more
"Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer." Sznol M et al., 2013 Mar 1, Clin Cancer Res Read more
"Assessing PDL-1 and PD-1 in Non-Small Cell Lung Cancer: A Novel Immunoscore Approach." Paulsen EE et al., 2017 Mar, Clin Lung Cancer Read more
"Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue." Liarski VM et al., 2014 Apr 2, Sci Transl Med Read more
"Clinicopathologic analysis of peripheral T-cell lymphoma, follicular variant, and comparison with angioimmunoblastic T-cell lymphoma: Bcl-6 expression might affect progression between these disorders." Miyoshi H et al., 2012 Jun, Am J Clin Pathol Read more
"Crucial Contributions by T Lymphocytes (Effector, Regulatory, and Checkpoint Inhibitor) and Cytokines (TH1, TH2, and TH17) to a Pathological Complete Response Induced by Neoadjuvant Chemotherapy in Women with Breast Cancer." Kaewkangsadan V et al., 2016, J Immunol Res Read more
"Defective B-cell memory in patients with Down syndrome." Verstegen RHJ et al., 2014 Dec, J Allergy Clin Immunol Read more
"Differential induction of PD-1/PD-L1 in Neuroimmune cells by drug of abuse." Mishra V et al., 2015, Int J Physiol Pathophysiol Pharmacol Read more
"Diffuse large B-cell lymphoma with a high number of epithelioid histiocytes (lymphoepithelioid B-cell lymphoma): a study of Osaka Lymphoma Study Group." Wada N et al., 2009 Sep, Virchows Arch Read more
"Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma." Roncador G et al., 2007 Aug, Haematologica Read more