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PEN2 antibody

Research Use Only
ORB2722
Biorbyt
ApplicationsELISA
DownloadDatasheet
Product group Antibodies
Price on request
Packing Size
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More than 130 suppliers
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Overview

  • Supplier
    Biorbyt
  • Product Name
    PEN2 antibody
  • Delivery Days Customer
    16
  • Applications
    ELISA
  • Applications Supplier
    WB: 1:500-2000, ELISA: 1:500-1000, IHC-P: 1:100-500, IF: 1:50-200 ELISA, IF, IHC-P, WB
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to PEN2. Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

References

  • Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice. Chu Y et al., 2015 Apr, Acta Biochim Biophys Sin (Shanghai)
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