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GTX132818 WB Image
GTX132818 WB Image
GTX132818 WB Image

Phospholamban (phospho Ser16) antibody

Research Use Only
GTX132818
GeneTex
Product group Antibodies
Price on request
Packing Size
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Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Phospholamban (phospho Ser16) antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.97 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203