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Phosphotyrosine antibody, MAb (HRP)

Research Use Only
ORB147706
Biorbyt
ApplicationsImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityAll Species
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    Phosphotyrosine antibody, MAb (HRP)
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Applications Supplier
    WB (1:1000), IHC (1:100) ICC, IP, WB, IHC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    G104
  • Concentration
    1 mg/ml
  • Conjugate
    HRP
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Mouse monoclonal to Phosphotyrosine (HRP). Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a proteins activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time. Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (4-6). In particular, the phosphorylation of tyrosine is considered one of the key steps in signal transduction and regulation of enzymatic activity. Phosphotyrosine can be detected through specific antibodies, and are helpful in facilitating the identification of tyrosine kinase substrates..
  • Reactivity
    All Species
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203