Overview
- SupplierGeneTex
- Product NamePKM antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.13 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). Liang YC et al., 2021 Dec, Am J PatholRead more
- -Characterization of pyruvate kinase from the anoxia tolerant turtle, Trachemys scripta elegans: a potential role for enzyme methylation during metabolic rate depression. Mattice AMS et al., 2018, PeerJRead more
- Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. May EW et al., 2014 Dec, Pharmacol ResRead more
- Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. Burman A et al., 2018 Aug 23, JCI InsightRead more
- Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma. Chang SJ et al., 2018 Jun 1, Arch Biochem BiophysRead more