PKMYT1 antibody [2B4] - Overexpression Validated

GeneTex

PKMYT1 antibody [2B4] - Overexpression Validated

10

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

2B4

1 mg/ml

Mouse

IgG

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on Thr-14. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on Tyr-15 to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Canine, Human, Monkey, Mouse, Rat

2°C to 8°C,-20°C

12352203