Overview
- SupplierGeneTex
- Product NamePKR antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.16 mg/ml
- IsotypeIgG
- Scientific DescriptionEIF2AK2 is a protein serine/threonine kinase that acquires enzymatic activity following autophosphorylation, a process mediated by double-stranded RNA (dsRNA). Activation of EIF2AK2 allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic protein synthesis initiation factor-2 (EIF2-alpha; MIM 603907), leading to the inhibition of protein synthesis (summary by Kuhen et al., 1996 [PubMed 8812437]).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203