POLE antibody

Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase epsilon. Sviderskiy VO et al., 2020 Nov 19, Mol Cell

POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. Bellelli R et al., 2018 Oct 4, Mol Cell

Polepsilon Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Bellelli R et al., 2018 May 17, Mol Cell

Validating the concept of mutational signatures with isogenic cell models. Zou X et al., 2018 May 1, Nat Commun