GTX113250 WB Image
GTX113250 WB Image
PPAR delta antibody [N2C3]
GTX113250
Product group Antibodies
Overview
- SupplierGeneTex
- Product NamePPAR delta antibody [N2C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.44 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions. Hyatt HW et al., 2019 Jan, Reprod SciRead more
- Lactation has persistent effects on a mothers metabolism and mitochondrial function. Hyatt HW et al., 2017 Dec 7, Sci RepRead more
- Physiological, mitochondrial, and oxidative stress differences in the presence or absence of lactation in rats. Hyatt HW et al., 2018 Jan 9, Reprod Biol EndocrinolRead more
- Yulink, predicted from evolutionary analysis, is involved in cardiac function. Kuo MW et al., 2021 Jan 11, J Biomed SciRead more