PTGER1 antibody, PAb

Biorbyt

PTGER1 antibody, PAb

16

Western Blot

0.1-0.5 μg/ml WB

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to PTGER1. PTGER1, Prostaglandin E Receptor 1, comprises 402 amino acids with a predicted molecular mass of 41,858 and has the 7 predicted transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptors activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

Hamster, Human

2°C to 8°C,-20°C

12352203