PTGS2 antibody, PAb

Biorbyt

PTGS2 antibody, PAb

16

Western Blot, ImmunoHistoChemistry

Western blot - 0.1-0.5 μg/ml - Human, Mouse - - - Immunohistochemistry(Paraffin-embedded Section) - 2-5 μg/ml - Human, Mouse - - - By Heat WB, IHC

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to PTGS2. Cyclooxygenase (Cox) is the key enzyme in conversion of arachidonic acid to PGs, and two isoforms, Cox-1 and Cox-2, have been identified. Cox-2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and other tumors. Deletion of the murine Cox-2 gene in Min mice reduced the incidence of intestinal tumors, suggesting that it is required for tumorigenesis. This gene is localized to sites associated with retinal blood vessels, and plays an important role in blood vessel formation in the retina. And the glucocorticoid receptor suppression of COX-2 is also crucial for curtailing lethal immune activation, and suggest new therapeutic approaches for regulation of T-cell-mediated inflammatory diseases.

Bovine, Human, Mouse

2°C to 8°C,-20°C

12352203