PUMA antibody - KO/KD Validated

GeneTex

PUMA antibody - KO/KD Validated

10

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

Rabbit

IgG

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Human, Mouse

2°C to 8°C,-20°C

12352203