GTX117364 ICC/IF Image
Purine nucleoside phosphorylase antibody
GTX117364
Product group Antibodies
Overview
- SupplierGeneTex
- Product NamePurine nucleoside phosphorylase antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Purine metabolism gene deregulation in Parkinsons disease. Garcia-Esparcia P et al., 2015 Dec, Neuropathol Appl NeurobiolRead more