Overview
- SupplierGeneTex
- Product NamePZP antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.65 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimers disease patients. [provided by RefSeq, Dec 2016]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimers-associated amyloid beta peptide. Cater JH et al., 2019 Mar 26, Proc Natl Acad Sci U S ARead more