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Rat IgG2c isotype control [SB68b]

Research Use Only
GTX35063
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Rat IgG2c isotype control [SB68b]
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SB68b
  • Concentration
    0.5 mg/ml
  • Host
    Rat
  • Isotype
    IgG
  • Scientific Description
    Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Zhang G et al., 2016 Feb 23, Proc Natl Acad Sci U S A
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