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GTX104052 IHC-P Image
GTX104052 IHC-P Image
GTX104052 IHC-P Image

RFC4 antibody [N1C3]

Research Use Only
GTX104052
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    RFC4 antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.62 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A proteomic characterization of factors enriched at nascent DNA molecules. Lopez-Contreras AJ et al., 2013 Apr 25, Cell Rep
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  • XLF and H2AX function in series to promote replication fork stability. Chen BR et al., 2019 Jul 1, J Cell Biol
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