Bio-Connect

RIF1 antibody, PAb

Research Use Only
ORB131891
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    RIF1 antibody, PAb
  • Delivery Days Customer
    10
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:3000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    100 ug/ml
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to RIF1. Telomere-associated protein RIF1 shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. RIF1 localizes to aberrant telomeres and may be involved in DNA repair. RIF1 is required for checkpoint mediated arrest of cell cycle progression in response to DNA damage during S-phase (the intra-S-phase checkpoint). This checkpoint requires activation of at least 2 parallel pathways by the ATM kinase: one involves the MRN (MRE11A-RAD50-NBS1) complex, while the second requires CHEK2. RIF1 seems to act independently of both pathways. RIF1 seems to play no role in either the G1/S or G2/M DNA damage checkpoints.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203