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GTX129789 WB Image
GTX129789 WB Image
GTX129789 WB Image

RNPS1 antibody

Research Use Only
GTX129789
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    RNPS1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Sumoylation is Required for the Cytoplasmic Accumulation of a Subset of mRNAs. Zhang H et al., 2014 Oct 20, Genes (Basel)
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  • XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence. Hou S et al., 2019 Sep 5, Nucleic Acids Res
    Read more