GTX114103 IHC-P Image
GTX114103 IHC-P Image
ROBO1 antibody
GTX114103
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameROBO1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.2 mg/ml
- IsotypeIgG
- Scientific DescriptionBilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Down-regulation of ROBO2 expression in prostate cancers. Choi YJ et al., 2014 Jul, Pathol Oncol ResRead more
- miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance. Yang T et al., 2018 Sep 4, Cell RepRead more
- Pharmacogenetics of response to neoadjuvant paclitaxel treatment for locally advanced breast cancer. Perez-Ortiz AC et al., 2017 Dec 5, OncotargetRead more