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GTX113004 WB Image
GTX113004 WB Image
GTX113004 WB Image

RPA32 antibody

Research Use Only
GTX113004
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPA32 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.64 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo. Parisotto M et al., 2018 Jun 4, J Exp Med
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