RPE65 antibody [401.8B11.3D9] - Orthogonal Validated

GeneTex

RPE65 antibody [401.8B11.3D9] - Orthogonal Validated

10

Flow Cytometry, ImmunoFluorescence, Mass Spectrometry, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

401.8B11.3D9

1 mg/ml

Mouse

IgG

Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Bovine, Canine, Chicken, Human, Mouse, Porcine, Rat, Xenopus

2°C to 8°C,-20°C

12352203