Overview
- SupplierGeneTex
- Product NameS100 beta antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.09 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimers disease, Downs syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- FcRgamma-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice. Ogawa Y et al., 2017 Jan 13, Sci RepRead more
- Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage. Kumagai K et al., 2020 Jul 23, Sci RepRead more
- Induction of neural crest cells from human dental pulp-derived induced pluripotent stem cells. Kawano E et al., 2017, Biomed ResRead more
- Neuroglia in the autistic brain: evidence from a preclinical model. Bronzuoli MR et al., 2018, Mol AutismRead more
- Pro-inflammatory AGE-RAGE signaling is activated during arousal from hibernation in ground squirrel adipose. Logan SM et al., 2018, PeerJRead more