S100B Antibody
ORB402954
Overview
- SupplierBiorbyt
- Product NameS100B Antibody
- Delivery Days Customer16
- ApplicationsImmunoFluorescence
- Applications SupplierImmunofluorescence: 1-2ug/ml,Immunohistology (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) IF, IHC-P
- CertificationResearch Use Only
- Clone IDPS1B1-1
- IsotypeIgG
- Scientific DescriptionS100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein. In the adult organism it is usually elevated due to nervous system damage, which makes it a potential clinical marker. [Wiki]
- UNSPSC12352203