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GTX131411 IHC-P Image
GTX131411 IHC-P Image
GTX131411 IHC-P Image

SARM1 antibody

Research Use Only
GTX131411
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    SARM1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.68 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Sarm1 induction and accompanying inflammatory response mediates age-dependent susceptibility to rotenone-induced neurotoxicity. Sur M et al., 2018, Cell Death Discov
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