Overview
- SupplierGeneTex
- Product NameSARM1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.68 mg/ml
- IsotypeIgG
- Scientific DescriptionInvolved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Sarm1 induction and accompanying inflammatory response mediates age-dependent susceptibility to rotenone-induced neurotoxicity. Sur M et al., 2018, Cell Death DiscovRead more