Sclerostin antibody [9N13]

GeneTex

Sclerostin antibody [9N13]

10

Western Blot

Research Use Only

Monoclonal

9N13

500 ug/ml

Mouse

IgG

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C,-20°C

12352203