Bio-Connect
GTX129852 WB Image
GTX129852 WB Image
GTX129852 WB Image

SEC61B antibody

Research Use Only
GTX129852
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SEC61B antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.77 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism. Chen MK et al., 2019 May 24, J Biol Chem
    Read more