GTX103712 IHC-P Image
GTX103712 IHC-P Image
Seladin 1 antibody [N1C2]
GTX103712
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSeladin 1 antibody [N1C2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.47 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Inhibition of DHCR24 increases the cisplatin-induced damage to cochlear hair cells in vitro. Tian KY et al., 2019 Jul 27, Neurosci LettRead more
- INPP5K and SIL1 associated pathologies with overlapping clinical phenotypes converge through dysregulation of PHGDH. Hathazi D et al., 2021 Sep 4, BrainRead more
- New Inhibitory Effect of Latilactobacillus sakei UONUMA on the Cholesterol Biosynthesis Pathway in Human HepG2 Cells. Ohta-Shimizu M et al., 2021, Biol Pharm BullRead more