SIGIRR antibody

GeneTex

SIGIRR antibody

10

Western Blot

Research Use Only

Polyclonal

Rabbit

IgG

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Human

2°C to 8°C,-20°C

12352203