Overview
- SupplierGeneTex
- Product NameSLUG antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells. Chen PC et al., 2018 Jun, J Cell PhysiolRead more
- Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5. Chen CY et al., 2018 Jan 27, Int J Mol SciRead more
- DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. Chen HH et al., 2021 Sep 24, iScienceRead more
- Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3beta/ZEB1 pathway. Lv F et al., 2021 Jun 5, Eur J PharmacolRead more
- PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition. Wang LT et al., 2020 Feb 5, EMBO RepRead more
- PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer LettRead more
- PEGylated liposome-encapsulated rhenium-188 radiopharmaceutical inhibits proliferation and epithelial-mesenchymal transition of human head and neck cancer cells in vivo with repeated therapy. Chang CY et al., 2018, Cell Death DiscovRead more
- Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. Wang LT et al., 2021 Nov 1, Cancer LettRead more
- Podocalyxin-Like Protein 1 Regulates TAZ Signaling and Stemness Properties in Colon Cancer. Lee WY et al., 2017 Sep 23, Int J Mol SciRead more
- Prognostic Value of a Glycolytic Signature and Its Regulation by Y-Box-Binding Protein 1 in Triple-Negative Breast Cancer. Lai YW et al., 2021 Jul 26, CellsRead more