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GTX115669 WB Image
GTX115669 WB Image
GTX115669 WB Image

SMC5 antibody [N2N3]

Research Use Only
GTX115669
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    SMC5 antibody [N2N3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes. Gomez R et al., 2013 Sep 15, J Cell Sci
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  • Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Murphy CM et al., 2016 Sep 13, Cell Rep
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  • SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes. Hwang G et al., 2017 May 1, Development
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