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GTX100554 WB Image
GTX100554 WB Image
GTX100554 WB Image

SOD1 antibody

Research Use Only
GTX100554
GeneTex
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Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    SOD1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.15 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

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  • 17beta-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma. Lin HY et al., 2021 Aug 20, Free Radic Biol Med
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  • 3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFkappaB Signaling Pathways. Chao W et al., 2017 Mar 28, Molecules
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  • Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys. Balhorn R et al., 2020 Jun 30, Int J Mol Sci
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  • Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, Nutrients
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  • Abeta exacerbates alpha-synuclein-induced neurotoxicity through impaired insulin signaling in alpha-synuclein-overexpressed human SK-N-MC neuronal cells. Chang CC et al., 2018 Jan, CNS Neurosci Ther
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  • Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress. Ramos H et al., 2020 Sep 10, Antioxidants (Basel)
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