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GTX100659 ICC/IF Image
GTX100659 ICC/IF Image
GTX100659 ICC/IF Image

SOD1 antibody

Research Use Only
GTX100659
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SOD1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.47 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Aldehyde dehydrogenase 2 protects against abdominal aortic aneurysm formation by reducing reactive oxygen species, vascular inflammation, and apoptosis of vascular smooth muscle cells. Tsai SH et al., 2020 Jul, FASEB J
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  • Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Tury A et al., 2014 Aug, Dev Neurobiol
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  • Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats. Chen HW et al., 2014 Oct 1, Toxicol Appl Pharmacol
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  • Exogenous C8-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells. Chang YC et al., 2018 Oct 2, Int J Mol Sci
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  • Hydrogen peroxide toxicity on auditory cells: An in vitro study. Gentilin E et al., 2021 Aug 25, Chem Biol Interact
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  • Melatonin Successfully Rescues the Hippocampal Molecular Machinery and Enhances Anti-oxidative Activity Following Early-Life Sleep Deprivation Injury. Chang HM et al., 2021 May 13, Antioxidants (Basel)
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  • Oral administration of Jumihaidokuto inhibits UVB-induced skin damage and prostaglandin E2 production in HR-1 hairless mice. Murata K et al., 2021 Jan, J Nat Med
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  • Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Chou CK et al., 2019 Apr, Environ Toxicol
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  • The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Liu W et al., 2020, Oxid Med Cell Longev
    Read more