Overview
- SupplierGeneTex
- Product NameSOD1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.47 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats. Chen HW et al., 2014 Oct 1, Toxicol Appl PharmacolRead more
- Exogenous C8-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells. Chang YC et al., 2018 Oct 2, Int J Mol SciRead more
- Hydrogen peroxide toxicity on auditory cells: An in vitro study. Gentilin E et al., 2021 Aug 25, Chem Biol InteractRead more
- Melatonin Successfully Rescues the Hippocampal Molecular Machinery and Enhances Anti-oxidative Activity Following Early-Life Sleep Deprivation Injury. Chang HM et al., 2021 May 13, Antioxidants (Basel)Read more
- Oral administration of Jumihaidokuto inhibits UVB-induced skin damage and prostaglandin E2 production in HR-1 hairless mice. Murata K et al., 2021 Jan, J Nat MedRead more
- Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Chou CK et al., 2019 Apr, Environ ToxicolRead more
- The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Liu W et al., 2020, Oxid Med Cell LongevRead more